Title : Fucosylated chondroitin sulfate from Acaudina molpadioides improves hyperglycemia via activation of PKB/GLUT4 signaling in skeletal muscle of insulin resistant mice.

Pub. Date : 2013 Nov

PMID : 24061149






1 Functional Relationships(s)
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1 Although the total protein expressions of IR-beta, IRS-1, PI3K, PKB and GLUT4 in skeletal muscle were not affected, insulin-stimulated GLUT4 translocation and phosphorylation of Tyr-IR-beta, Tyr612-IRS-1, p85-PI3K, Ser473-PKB, and Thr308-PKB were significantly increased by CHS supplement. Tyrosine insulin receptor substrate 1 Mus musculus