Cholesterol

nuclear receptor subfamily 1 group H member 3 ; Homo sapiens







188 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
51 28082258 EEPD1 Is a Novel LXR Target Gene in Macrophages Which Regulates ABCA1 Abundance and Cholesterol Efflux. 2017 Mar 2
52 28356389 Liver carcinogenesis by FOS-dependent inflammation and cholesterol dysregulation. 2017 May 1 1
53 28499814 Selected cholesterol biosynthesis inhibitors produce accumulation of the intermediate FF-MAS that targets nucleus and activates LXRα in HepG2 cells. 2017 Sep 1
54 28673011 Tribbles homolog 1 enhances cholesterol efflux from oxidized low-density lipoprotein-loaded THP-1 macrophages. 2017 Jul 1
55 28781617 Interleukin-32 promotes lipid accumulation through inhibition of cholesterol efflux. 2017 Aug 1
56 28989932 MUTATIONS IN LIVER X RECEPTOR ALPHA THAT IMPAIR DIMERIZATION AND LIGAND DEPENDENT TRANSACTIVATION. 2017 1
57 26692490 Transcriptional regulation of the human Liver X Receptor α gene by Hepatocyte Nuclear Factor 4α. 2016 Jan 15 1
58 26722214 Excess Nitric Oxide Activates TRPV1-Ca(2+)-Calpain Signaling and Promotes PEST-dependent Degradation of Liver X Receptor α. 2016 1
59 26725543 Evidence of deregulated cholesterol efflux in abdominal aortic aneurysm. 2016 Mar 1
60 27592060 The cytotoxicity of 27-hydroxycholesterol in co-cultured SH-SY5Y cells and C6 cells. 2016 Oct 6 1
61 27735019 Quercetin upregulates ABCA1 expression through liver X receptor alpha signaling pathway in THP-1 macrophages. 2016 Sep 1
62 28096801 Protective Effects of Platycodin D on Lipopolysaccharide-Induced Acute Lung Injury by Activating LXRα-ABCA1 Signaling Pathway. 2016 1
63 28105139 Baicalin promotes cholesterol efflux by regulating the expression of SR-BI in macrophages. 2016 Dec 2
64 25334019 Fibroblast growth factor 21 enhances cholesterol efflux in THP-1 macrophage-derived foam cells. 2015 Jan 1
65 25496323 Alpinetin enhances cholesterol efflux and inhibits lipid accumulation in oxidized low-density lipoprotein-loaded human macrophages. 2015 Nov-Dec 4
66 25600616 Propofol up-regulates expression of ABCA1, ABCG1, and SR-B1 through the PPARγ/LXRα signaling pathway in THP-1 macrophage-derived foam cells. 2015 Jul-Aug 3
67 25755733 Adiponectin upregulates ABCA1 expression through liver X receptor alpha signaling pathway in RAW 264.7 macrophages. 2015 1
68 25779847 Angiotensin-(1-7) stimulates cholesterol efflux from angiotensin II-treated cholesterol-loaded THP-1 macrophages through the suppression of p38 and c-Jun N-terminal kinase signaling. 2015 Jul 1
69 25956064 Salvianolic acid B accelerated ABCA1-dependent cholesterol efflux by targeting PPAR-γ and LXRα. 2015 Jul 3 1
70 26015858 Mitochondrial function and regulation of macrophage sterol metabolism and inflammatory responses. 2015 May 26 2
71 26102194 Curcumin enhanced cholesterol efflux by upregulating ABCA1 expression through AMPK-SIRT1-LXRα signaling in THP-1 macrophage-derived foam cells. 2015 Sep 2
72 26113985 Capsaicin may have important potential for promoting vascular and metabolic health. 2015 1
73 26261553 Lipoxin A4 promotes ABCA1 expression and cholesterol efflux through the LXRα signaling pathway in THP-1 macrophage-derived foam cells. 2015 2
74 26264562 Lycopene reduces cholesterol absorption through the downregulation of Niemann-Pick C1-like 1 in Caco-2 cells. 2015 Nov 1
75 26475038 Saikosaponin a inhibits lipopolysaccharide-oxidative stress and inflammation in Human umbilical vein endothelial cells via preventing TLR4 translocation into lipid rafts. 2015 Dec 2
76 26551724 Liver X receptors in immune cell function in humans. 2015 Aug 1
77 26603933 Glucagon-like peptide 1 (GLP-1)-based therapy upregulates LXR-ABCA1/ABCG1 cascade in adipocytes. 2015 Dec 25 2
78 26670369 Pravastatin Modulate Niemann-Pick C1-Like 1 and ATP-Binding Cassette G5 and G8 to Influence Intestinal Cholesterol Absorption. 2015 1
79 24334278 Identification of a selective agonist for liver X receptor α (LXRα) via screening of a synthetic compound library. 2014 Apr 1
80 24372550 Differential interactions of antiretroviral agents with LXR, ER and GR nuclear receptors: potential contributing factors to adverse events. 2014 Jan 1
81 24603323 miR-206 controls LXRα expression and promotes LXR-mediated cholesterol efflux in macrophages. 2014 Jun 2
82 24704452 22(R)-hydroxycholesterol and pioglitazone synergistically decrease cholesterol ester via the PPARγ-LXRα-ABCA1 pathway in cholesterosis of the gallbladder. 2014 Apr 25 2
83 24735204 FGF21 increases cholesterol efflux by upregulating ABCA1 through the ERK1/2-PPARγ-LXRα pathway in THP1 macrophage-derived foam cells. 2014 Aug 3
84 24751522 miR-613 regulates cholesterol efflux by targeting LXRα and ABCA1 in PPARγ activated THP-1 macrophages. 2014 Jun 6 2
85 24947527 Macrophage-independent regulation of reverse cholesterol transport by liver X receptors. 2014 Aug 2
86 24996838 Cholesterol efflux is LXRα isoform-dependent in human macrophages. 2014 Jul 4 4
87 25011264 [Effect of ligustrazine on reverse cholesterol transport in foam cells]. 2014 Apr 1
88 25035925 Interleukin-10 increases reverse cholesterol transport in macrophages through its bidirectional interaction with liver X receptor α. 2014 Aug 8 2
89 25225013 Angiotensin-(1-7) upregulates expression of adenosine triphosphate-binding cassette transporter A1 and adenosine triphosphate-binding cassette transporter G1 through the Mas receptor through the liver X receptor alpha signalling pathway in THP-1 macrophages treated with angiotensin-II. 2014 Dec 2
90 25450668 Identification of a novel partial agonist of liver X receptor α (LXRα) via screening. 2014 Dec 1 1
91 23313547 Knock-down of the oxysterol receptor LXRα impairs cholesterol efflux in human primary macrophages: lack of compensation by LXRβ activation. 2013 Jul 1 2
92 23393188 Genome-wide analysis of LXRα activation reveals new transcriptional networks in human atherosclerotic foam cells. 2013 Apr 1 1
93 23451202 Foam cell specific LXRα ligand. 2013 1
94 23658787 Nicotinic acid receptor GPR109A is down-regulated in human macrophage-derived foam cells. 2013 1
95 23686114 Differential regulation of gene expression by LXRs in response to macrophage cholesterol loading. 2013 Jul 3
96 23732298 Dual roles of nuclear receptor liver X receptor α (LXRα) in the CYP3A4 expression in human hepatocytes as a positive and negative regulator. 2013 Aug 1 2
97 23812592 Nifedipine enhances cholesterol efflux in RAW264.7 macrophages. 2013 Oct 3
98 22052915 Activating transcription factor 1 directs Mhem atheroprotective macrophages through coordinated iron handling and foam cell protection. 2012 Jan 6 1
99 22098164 Inflammatory stress exacerbates hepatic cholesterol accumulation via disrupting cellular cholesterol export. 2012 May 1
100 22137263 Lycopene and the LXRα agonist T0901317 synergistically inhibit the proliferation of androgen-independent prostate cancer cells via the PPARγ-LXRα-ABCA1 pathway. 2012 Sep 1