Pub. Date : 2013 Jul
PMID : 23686114
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | For instance, the accumulation of excess cholesterol by macrophages initiates a genetic response mediated by the liver X receptors (LXRs)-alpha (NR1H3) and LXRbeta (NR1H2), which facilitates the transport of cholesterol out of cells to high-density lipoprotein particles. | Cholesterol | nuclear receptor subfamily 1 group H member 3 | Homo sapiens |
| 2 | For instance, the accumulation of excess cholesterol by macrophages initiates a genetic response mediated by the liver X receptors (LXRs)-alpha (NR1H3) and LXRbeta (NR1H2), which facilitates the transport of cholesterol out of cells to high-density lipoprotein particles. | Cholesterol | nuclear receptor subfamily 1 group H member 3 | Homo sapiens |
| 3 | The gene-selective response to cholesterol loading occurs, even in the presence of LXRalpha binding to the promoter of the gene encoding the sterol regulatory element-binding protein-1c, the master transcriptional regulator of fatty acid synthesis. | Cholesterol | nuclear receptor subfamily 1 group H member 3 | Homo sapiens |