Title : Genome-wide analysis of LXRα activation reveals new transcriptional networks in human atherosclerotic foam cells.

Pub. Date : 2013 Apr 1

PMID : 23393188






1 Functional Relationships(s)
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1 These observations identified highly integrated LXRalpha ligand-dependent transcriptional networks, including the APOE/C1/C4/C2-gene cluster, which contribute to the reversal of cholesterol efflux and the dampening of inflammation processes in foam cells to prevent atherogenesis. Cholesterol nuclear receptor subfamily 1 group H member 3 Homo sapiens