Title : Nifedipine enhances cholesterol efflux in RAW264.7 macrophages.

Pub. Date : 2013 Oct

PMID : 23812592






3 Functional Relationships(s)
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Protein Name
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1 SiRNA-mediated silencing of LXRalpha revealed that LXRalpha was involved in these increases and the enhanced cholesterol efflux. Cholesterol nuclear receptor subfamily 1 group H member 3 Homo sapiens
2 SiRNA-mediated silencing of LXRalpha revealed that LXRalpha was involved in these increases and the enhanced cholesterol efflux. Cholesterol nuclear receptor subfamily 1 group H member 3 Homo sapiens
3 CONCLUSION: Nifedipine may protect against atherosclerosis partly by promoting macrophage cholesterol efflux through the stimulation of LXRalpha-dependent expression of ABCA1, ABCG1, and SR-BI. Cholesterol nuclear receptor subfamily 1 group H member 3 Homo sapiens