Title : Dietary geranylgeraniol can limit the activity of pitavastatin as a potential treatment for drug-resistant ovarian cancer.

Pub. Date : 2017 Jul 14

PMID : 28710496






1 Functional Relationships(s)
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1 Pitavastatin-induced apoptosis was blocked by geranylgeraniol and mevalonate, products of the HMGCR pathway, confirming that pitavastatin causes cell death through inhibition of HMGCR. Mevalonic Acid 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens