Title : Identifying Potential Therapeutics for Osteoporosis by Exploiting the Relationship between Mevalonate Pathway and Bone Metabolism.

Pub. Date : 2018

PMID : 29683099






1 Functional Relationships(s)
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1 Statins, a well-known class of cholesterol-lowering agents, inhibit 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase, the rate-determining enzyme in the mevalonate pathway. Mevalonic Acid 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens