Title : Fluvastatin protects cochleae from damage by high-level noise.

Pub. Date : 2018 Feb 14

PMID : 29445111






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Using Auditory Brainstem Responses (ABR) in a guinea pig model, we demonstrate that fluvastatin, an inhibitor of HMG-CoA reductase, the rate-limiting enzyme of the mevalonate pathway, protects against loss of cochlear function initiated by high intensity noise. Mevalonic Acid 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens