Title : Fluvastatin Inhibits HMG-CoA Reductase and Prevents Non-Small Cell Lung Carcinogenesis.

Pub. Date : 2019 Dec

PMID : 31554629






1 Functional Relationships(s)
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1 In this study, we found that fluvastatin targeted 3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase (HMGCR), which a rate-limiting enzyme in the mevalonate pathway, and inhibited non-small cell lung cancer (NSCLC) tumorigenesis. Mevalonic Acid 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens