Title : Transcriptome-based identification of lovastatin as a breast cancer stem cell-targeting drug.

Pub. Date : 2019 Jun

PMID : 31026757






2 Functional Relationships(s)
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Protein Name
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1 Mevalonate mitigated the effects of lovastatin, suggesting that the targeting of CSCs by lovastatin was mediated by the inhibition of its reported target, 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMGCR). Mevalonic Acid 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens
2 Mevalonate mitigated the effects of lovastatin, suggesting that the targeting of CSCs by lovastatin was mediated by the inhibition of its reported target, 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMGCR). Mevalonic Acid 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens