Title : Mevalonate signaling, COPD and cancer: the statins and beyond.

Pub. Date : 2019 Apr

PMID : 30787037






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The mevalonate pathway is modifiable through the enzyme 3-hydroxy-3-methyl-glutaryl-Coenzyme A (HMGCo-A) reductase. Mevalonic Acid 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens
2 This enzyme controls the rate limiting step of the mevalonate pathway and is subject to inhibition by statin drugs (HMGCo-A reductase inhibitors) and small chain fatty acids derived from high dietary fiber intake. Mevalonic Acid 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens