Pub. Date : 2019 Oct
PMID : 31455613
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Endogenous sterol intermediates of the mevalonate pathway regulate HMG-CoA reductase degradation and SREBP-2 processing. | Mevalonic Acid | 3-hydroxy-3-methylglutaryl-CoA reductase | Homo sapiens |
| 2 | With a constructed HeLa cell line expressing the mevalonate transporter, we individually deleted genes encoding major enzymes in the mevalonate pathway, used lipidomics to measure sterol intermediates, and examined HMGCR and SREBP-2 statuses. | Mevalonic Acid | 3-hydroxy-3-methylglutaryl-CoA reductase | Homo sapiens |