FK506 binding protein 1b ; Mus musculus






28 Article(s)
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1 11258666 Signal transduction from bradykinin, angiotensin, adrenergic and muscarinic receptors to effector enzymes, including ADP-ribosyl cyclase. Biol Chem 2001 Jan 1
2 11907581 Oestrogen protects FKBP12.6 null mice from cardiac hypertrophy. Nature 2002 Mar 21 2
3 15036951 Role of FKBP12.6 in hypoxia- and norepinephrine-induced Ca2+ release and contraction in pulmonary artery myocytes. Cell Calcium 2004 Apr 5
4 16191273 [Effect of carvedilol on ryanodine receptor in heart failure]. Zhonghua Er Ke Za Zhi 2005 Aug 1
5 16407108 Ryanodine receptor/calcium release channel PKA phosphorylation: a critical mediator of heart failure progression. Proc Natl Acad Sci U S A 2006 Jan 17 1
6 16481613 Analysis of calstabin2 (FKBP12.6)-ryanodine receptor interactions: rescue of heart failure by calstabin2 in mice. Proc Natl Acad Sci U S A 2006 Feb 28 3
7 16672364 Stabilization of cardiac ryanodine receptor prevents intracellular calcium leak and arrhythmias. Proc Natl Acad Sci U S A 2006 May 16 2
8 17261647 FK506 binding protein 12/12.6 depletion increases endothelial nitric oxide synthase threonine 495 phosphorylation and blood pressure. Hypertension 2007 Mar 2
9 17478757 Removal of FKBP12/12.6 from endothelial ryanodine receptors leads to an intracellular calcium leak and endothelial dysfunction. Arterioscler Thromb Vasc Biol 2007 Jul 2
10 18466757 FKBP12.6 disruption impairs glucose-induced insulin secretion. Biochem Biophys Res Commun 2008 Jul 11 4
11 18598963 Intracellular calcium leak due to FKBP12.6 deficiency in mice facilitates the inducibility of atrial fibrillation. Heart Rhythm 2008 Jul 2
12 19578067 Dissociation of FKBP12.6 from ryanodine receptor type 2 is regulated by cyclic ADP-ribose but not beta-adrenergic stimulation in mouse cardiomyocytes. Cardiovasc Res 2009 Nov 1 1
13 19805579 FKBP12.6-knockout mice display hyperinsulinemia and resistance to high-fat diet-induced hyperglycemia. FASEB J 2010 Feb 5
14 20451249 Ca(2+) release induced by cADP-ribose is mediated by FKBP12.6 proteins in mouse bladder smooth muscle. Cell Calcium 2010 May 1
15 20676041 Characterization of a novel mutation in the cardiac ryanodine receptor that results in catecholaminergic polymorphic ventricular tachycardia. Channels (Austin) 2010 Jul-Aug 1
16 20797399 Limitations of FKBP12.6-directed treatment strategies for maladaptive cardiac remodeling and heart failure. J Mol Cell Cardiol 2011 Jan 3
17 21099115 Role of chronic ryanodine receptor phosphorylation in heart failure and β-adrenergic receptor blockade in mice. J Clin Invest 2010 Dec 1
18 21924056 [Effect of carvedilol and Radix astragali on ryanodine receptor in heart failure in mice]. Zhonghua Er Ke Za Zhi 2011 Jun 1
19 22087651 Transgenic analysis of the role of FKBP12.6 in cardiac function and intracellular calcium release. Assay Drug Dev Technol 2011 Dec 2
20 22311731 Cardiac FKBP12.6 overexpression protects against triggered ventricular tachycardia in pressure overloaded mouse hearts. Basic Res Cardiol 2012 Mar 2
21 22408025 Transcription factor CHF1/Hey2 regulates EC coupling and heart failure in mice through regulation of FKBP12.6. Am J Physiol Heart Circ Physiol 2012 May 1 2
22 23828045 Global gene expression profiling of pancreatic islets in mice during streptozotocin-induced β-cell damage and pancreatic Glp-1 gene therapy. Dis Model Mech 2013 Sep 1
23 23887639 Sirolimus-FKBP12.6 impairs endothelial barrier function through protein kinase C-α activation and disruption of the p120-vascular endothelial cadherin interaction. Arterioscler Thromb Vasc Biol 2013 Oct 1
24 25619687 Palmitoyl-carnitine increases RyR2 oxidation and sarcoplasmic reticulum Ca2+ leak in cardiomyocytes: Role of adenine nucleotide translocase. Biochim Biophys Acta 2015 May 1
25 25911196 Nonenzymatic lipid mediators, neuroprostanes, exert the antiarrhythmic properties of docosahexaenoic acid. Free Radic Biol Med 2015 Sep 4
26 28631094 Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits. Acta Neuropathol 2017 Nov 1
27 30046369 Propofol Protects Hippocampal Neurons from Hypoxia-Reoxygenation Injury by Decreasing Calcineurin-Induced Calcium Overload and Activating YAP Signaling. Oxid Med Cell Longev 2018 3
28 31626909 Stachydrine hydrochloride alleviates pressure overload-induced heart failure and calcium mishandling on mice. J Ethnopharmacol 2020 Feb 10 1