Title : [Effect of carvedilol and Radix astragali on ryanodine receptor in heart failure in mice].

Pub. Date : 2011 Jun

PMID : 21924056






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Carvedilol and Radix astragali can increase expression of RyR2 mRNA and inhibit Ca(2+) leak by restoring the binding of FKBP12.6 back to RyR in HF to improve cardiac function and prevent left ventricle from remodeling. Carvedilol FK506 binding protein 1b Mus musculus