Title : Role of chronic ryanodine receptor phosphorylation in heart failure and β-adrenergic receptor blockade in mice.

Pub. Date : 2010 Dec

PMID : 21099115






1 Functional Relationships(s)
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1 Treatment with S107, a 1,4-benzothiazepine derivative that stabilizes RyR2-calstabin2 interactions, inhibited the RyR2-mediated diastolic SR Ca2+ leak and reduced HF progression in WT and RyR2-S2808D+/+ mice. 1,4-Benzothiazepine FK506 binding protein 1b Mus musculus