Pub. Date : 2012 Mar
PMID : 22311731
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Cardiac FKBP12.6 overexpression protects against myocardial infarction-induced HF and catecholamine-promoted ventricular arrhythmias. | Catecholamines | FK506 binding protein 1b | Mus musculus |
2 | Cardiac FKBP12.6 overexpression in the mouse blunts pressure overload-induced maladaptive LV remodelling and protects against catecholamine-promoted burst pacing-induced ventricular tachycardia by decreasing cardiac sensitivity to adrenergic stress and RyR2 S2814 phosphorylation, and decreasing NCX1 activity. | Catecholamines | FK506 binding protein 1b | Mus musculus |