Pub. Date : 2004 Apr
PMID : 15036951
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Role of FKBP12.6 in hypoxia- and norepinephrine-induced Ca2+ release and contraction in pulmonary artery myocytes. | Norepinephrine | FK506 binding protein 1b | Mus musculus |
| 2 | Hypoxic Ca(2+) response and hypoxic vasoconstriction were significantly enhanced in FKBP12.6 knockout mouse PASMCs. | pasmcs | FK506 binding protein 1b | Mus musculus |
| 3 | Norepinephrine-induced Ca(2+) release and force generation were also markedly enhanced in PASMCs from FKBP12.6 null mice. | Norepinephrine | FK506 binding protein 1b | Mus musculus |
| 4 | Norepinephrine-induced Ca(2+) release and force generation were also markedly enhanced in PASMCs from FKBP12.6 null mice. | pasmcs | FK506 binding protein 1b | Mus musculus |
| 5 | These findings suggest that FKBP12.6 plays an important role in hypoxia- and neurotransmitter-induced Ca(2+) and contractile responses by regulating the activity of RyRs in PASMCs. | pasmcs | FK506 binding protein 1b | Mus musculus |