Janus kinase 2 ; Rattus norvegicus






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1 7508935 Activation of receptor-associated tyrosine kinase JAK2 by prolactin. J Biol Chem 1994 Feb 18 8
2 7510676 Rapid changes in nuclear protein tyrosine phosphorylation after growth hormone treatment in vivo. Identification of phosphorylated mitogen-activated protein kinase and STAT91. J Biol Chem 1994 Mar 18 1
3 7518927 Prolactin activates the interferon-regulated p91 transcription factor and the Jak2 kinase by tyrosine phosphorylation. Proc Natl Acad Sci U S A 1994 Jul 19 2
4 7535894 Binding of a growth hormone-inducible nuclear factor is mediated by tyrosine phosphorylation. Mol Endocrinol 1994 Dec 1
5 7545168 Growth hormone-dependent phosphorylation of tyrosine 333 and/or 338 of the growth hormone receptor. J Biol Chem 1995 Sep 15 3
6 7559450 Characterization of active and inactive forms of the JAK2 protein-tyrosine kinase produced via the baculovirus expression vector system. J Biol Chem 1995 Sep 29 10
7 7588246 Tyrosine phosphorylation of the growth hormone (GH) receptor and Janus tyrosine kinase-2 is involved in the insulin-like actions of GH in primary rat adipocytes. Endocrinology 1995 Nov 2
8 7746328 Direct stimulation of Jak/STAT pathway by the angiotensin II AT1 receptor. Nature 1995 May 18 2
9 8063815 Domains of the growth hormone receptor required for association and activation of JAK2 tyrosine kinase. J Biol Chem 1994 Aug 26 1
10 8703019 Insulin induces tyrosine phosphorylation of JAK2 in insulin-sensitive tissues of the intact rat. J Biol Chem 1996 Sep 6 5
11 8770909 Growth hormone stimulates tyrosine phosphorylation of JAK2 and STAT5, but not insulin receptor substrate-1 or SHC proteins in liver and skeletal muscle of normal rats in vivo. Endocrinology 1996 Jul 4
12 8813644 Possible involvement of Janus kinase Jak2 in interferon-gamma induction of nitric oxide synthase in rat glial cells. Eur J Pharmacol 1996 Jun 13 3
13 8892312 Contrasting acute in vivo nuclear actions of growth hormone and prolactin. Mol Cell Endocrinol 1996 Aug 9 1
14 8987828 Influence of cocaine on the JAK-STAT pathway in the mesolimbic dopamine system. J Neurosci 1996 Dec 15 2
15 9169451 Identification and localization of a skeletal muscle secrotonin 5-HT2A receptor coupled to the Jak/STAT pathway. J Biol Chem 1997 Jun 6 3
16 9207201 Prolactin-mediated inhibition of 20alpha-hydroxysteroid dehydrogenase gene expression and the tyrosine kinase system. Biochem Biophys Res Commun 1997 Jun 27 2
17 9287353 Dependence on the motif YIPP for the physical association of Jak2 kinase with the intracellular carboxyl tail of the angiotensin II AT1 receptor. J Biol Chem 1997 Sep 12 3
18 9299374 The type I angiotensin II receptor couples to Stat1 and Stat3 activation through Jak2 kinase in neonatal rat cardiac myocytes. J Mol Cell Cardiol 1997 Sep 2
19 9314595 In vivo study of prolactin (PRL) intracellular signalling during lactogenesis in the rat: JAK/STAT pathway is activated by PRL in the mammary gland but not in the liver. Biol Reprod 1997 Oct 1
20 9314843 Role of angiotensin II in activation of the JAK/STAT pathway induced by acute pressure overload in the rat heart. Circ Res 1997 Oct 2
21 9351438 Leukemia inhibitory factor, a potent cardiac hypertrophic cytokine, activates the JAK/STAT pathway in rat cardiomyocytes. Circ Res 1997 Nov 1
22 9419340 Nitric oxide and thiol redox regulation of Janus kinase activity. Proc Natl Acad Sci U S A 1998 Jan 6 8
23 9528967 Desensitization of the growth hormone-induced Janus kinase 2 (Jak 2)/signal transducer and activator of transcription 5 (Stat5)-signaling pathway requires protein synthesis and phospholipase C. Endocrinology 1998 Apr 6
24 9593046 Rapid induction of Jak2 and Sp1 in T cells by phosphorothioate oligonucleotides. Antisense Nucleic Acid Drug Dev 1998 Apr 1
25 9602424 Angiotensin II activates Stat5 through Jak2 kinase in cardiac myocytes. J Mol Cell Cardiol 1998 Apr 3
26 9685210 In vitro interaction between STAT 5 and JAK 2; dependence upon phosphorylation status of STAT 5 and JAK 2. Mol Cell Endocrinol 1998 Mar 16 1
27 9722518 Activation of the Janus kinase/signal transducer and activator of transcription pathway by osmotic shock. J Biol Chem 1998 Sep 4 1
28 9790227 GH signalling in pancreatic beta-cells. Endocr J 1998 Apr 1
29 9886807 Growth hormone stimulates the tyrosine kinase activity of JAK2 and induces tyrosine phosphorylation of insulin receptor substrates and Shc in rat tissues. Endocrinology 1999 Jan 6
30 9892011 Termination of growth hormone pulse-induced STAT5b signaling. Mol Endocrinol 1999 Jan 9
31 9973252 Down-regulation of liver JAK2-STAT5b signaling by the female plasma pattern of continuous growth hormone stimulation. Mol Endocrinol 1999 Feb 3
32 10203355 Inducible nitric oxide synthase can be induced in the absence of active nuclear factor-kappaB in rat mesangial cells: involvement of the Janus kinase 2 signaling pathway. J Am Soc Nephrol 1999 Apr 8
33 10432321 Role of the Janus kinase (JAK)/signal transducters and activators of transcription (STAT) cascade in advanced glycation end-product-induced cellular mitogenesis in NRK-49F cells. Biochem J 1999 Aug 15 3
34 10462502 Transcriptional suppression of rat angiotensin AT1a receptor gene expression by interferon-gamma in vascular smooth muscle cells. Biochem Biophys Res Commun 1999 Aug 27 1
35 10499497 The expression of interleukin-6 (IL-6), IL-6 receptor, and gp130-kilodalton glycoprotein in the rat decidua and a decidual cell line: regulation by 17beta-estradiol and prolactin. Endocrinology 1999 Oct 1
36 10585851 Stimulation of pancreatic beta-cell proliferation by growth hormone is glucose-dependent: signal transduction via janus kinase 2 (JAK2)/signal transducer and activator of transcription 5 (STAT5) with no crosstalk to insulin receptor substrate-mediated mitogenic signalling. Biochem J 1999 Dec 15 4
37 10585879 Role of janus kinase-2 in insulin-mediated phosphorylation and inactivation of protein phosphatase-2A and its impact on upstream insulin signalling components. Biochem J 1999 Dec 15 13
38 10600634 Stimulation of c-Src by prolactin is independent of Jak2. Biochem J 2000 Jan 1 1
39 10601634 Hypertrophic stimuli augment expression of cMG1/ERF-1, a putative zinc-finger motif transcription factor, in rat cardiomyocytes. FEBS Lett 1999 Dec 10 1
40 10707961 Thyrotropin induces SOCS-1 (suppressor of cytokine signaling-1) and SOCS-3 in FRTL-5 thyroid cells. Mol Endocrinol 2000 Mar 1
41 10809230 Involvement of JAK/STAT (Janus kinase/signal transducer and activator of transcription) in the thyrotropin signaling pathway. Mol Endocrinol 2000 May 2
42 10830295 Thyrotropin modulates interferon-gamma-mediated intercellular adhesion molecule-1 gene expression by inhibiting Janus kinase-1 and signal transducer and activator of transcription-1 activation in thyroid cells. Endocrinology 2000 Jun 2
43 10856262 Cardiotrophin-1 increases angiotensinogen mRNA in rat cardiac myocytes through STAT3 : an autocrine loop for hypertrophy. Hypertension 2000 Jun 1
44 10867506 Analysis of the prolongation of rat eosinophil survival induced by recombinant rat interleukin-5. Int Arch Allergy Immunol 2000 May 1
45 10884366 Role of the JAK/STAT pathway in rat carotid artery remodeling after vascular injury. Circ Res 2000 Jul 7 1
46 10965905 Insulin receptor substrate-1-mediated enhancement of growth hormone-induced mitogen-activated protein kinase activation. Endocrinology 2000 Sep 1
47 10976913 Mutation of the SHP-2 binding site in growth hormone (GH) receptor prolongs GH-promoted tyrosyl phosphorylation of GH receptor, JAK2, and STAT5B. Mol Endocrinol 2000 Sep 2
48 10991939 Role of the cytokine-inducible SH2 protein CIS in desensitization of STAT5b signaling by continuous growth hormone. J Biol Chem 2000 Dec 15 3
49 11032244 Regulation of cardiac Jak-2 in animal models of insulin resistance. IUBMB Life 2000 Jun 8
50 11064147 Activation of the Jak/Stat signal transduction pathway in GH-treated rat osteoblast-like cells in culture. Mol Cell Endocrinol 2000 Oct 25 2