Title : Influence of cocaine on the JAK-STAT pathway in the mesolimbic dopamine system.

Pub. Date : 1996 Dec 15

PMID : 8987828






2 Functional Relationships(s)
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Protein Name
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1 There is an increase in immunoreactivity of Janus kinase (JAK2), a CNTF-regulated protein tyrosine kinase, in the VTA after chronic but not acute cocaine administration. Cocaine Janus kinase 2 Rattus norvegicus
2 Double-labeling immunohistochemical studies show that JAK2 immunoreactivity in the VTA is enriched in dopaminergic and nondopaminergic cells, both of which exhibit increased JAK2 immunoreactivity after chronic cocaine treatment. Cocaine Janus kinase 2 Rattus norvegicus