Title : Domains of the growth hormone receptor required for association and activation of JAK2 tyrosine kinase.

Pub. Date : 1994 Aug 26

PMID : 8063815






1 Functional Relationships(s)
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1 In studies performed in CHO and RIN-5AH cells, the ability of JAK2 to associate with the mutated GHR was found to correlate with GH-dependent activation of JAK2, tyrosyl phosphorylation of GHR (in the case of GHR1-638 and GHR1-454), and the ability of the GHR to copurify with tyrosine kinase activity. cyclo(tyrosyl-tyrosyl) Janus kinase 2 Rattus norvegicus