Pub. Date : 1999 Jan
PMID : 9886807
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Growth hormone stimulates the tyrosine kinase activity of JAK2 and induces tyrosine phosphorylation of insulin receptor substrates and Shc in rat tissues. | Tyrosine | Janus kinase 2 | Rattus norvegicus |
| 2 | GH increased the tyrosine phosphorylation of IRS-1, IRS-2, JAK2, and Shc proteins in the liver, heart, kidney, muscle, and adipose tissue of rats. | Tyrosine | Janus kinase 2 | Rattus norvegicus |
| 3 | The correlation between JAK2 tyrosyl phosphorylation and IRS-1 tyrosyl phosphorylation in response to GH together with the results of the in vitro tyrosine kinase assay are consistent with the hypothesis that JAK2 may mediate GH-induced phosphorylation of IRS-1. | cyclo(tyrosyl-tyrosyl) | Janus kinase 2 | Rattus norvegicus |
| 4 | The correlation between JAK2 tyrosyl phosphorylation and IRS-1 tyrosyl phosphorylation in response to GH together with the results of the in vitro tyrosine kinase assay are consistent with the hypothesis that JAK2 may mediate GH-induced phosphorylation of IRS-1. | cyclo(tyrosyl-tyrosyl) | Janus kinase 2 | Rattus norvegicus |
| 5 | The correlation between JAK2 tyrosyl phosphorylation and IRS-1 tyrosyl phosphorylation in response to GH together with the results of the in vitro tyrosine kinase assay are consistent with the hypothesis that JAK2 may mediate GH-induced phosphorylation of IRS-1. | cyclo(tyrosyl-tyrosyl) | Janus kinase 2 | Rattus norvegicus |
| 6 | The correlation between JAK2 tyrosyl phosphorylation and IRS-1 tyrosyl phosphorylation in response to GH together with the results of the in vitro tyrosine kinase assay are consistent with the hypothesis that JAK2 may mediate GH-induced phosphorylation of IRS-1. | cyclo(tyrosyl-tyrosyl) | Janus kinase 2 | Rattus norvegicus |