| 1 | 1737752 | Low structural specificity for nucleoside triphosphates as antagonists of ADP-induced platelet activation. | J Biol Chem | 1992 Feb 15 |
2 |
| 2 | 7945429 | Effects of extracellular divalent cations on responses of human blood platelets to adenosine 5'-diphosphate. | Biochem Pharmacol | 1994 Oct 7 |
2 |
| 3 | 9653141 | Coactivation of two different G protein-coupled receptors is essential for ADP-induced platelet aggregation. | Proc Natl Acad Sci U S A | 1998 Jul 7 |
1 |
| 4 | 10440415 | Single-dose pharmacodynamics of clopidogrel. | Semin Thromb Hemost | 1999 |
1 |
| 5 | 10440416 | Repeated-dose pharmacodynamics of clopidogrel in healthy subjects. | Semin Thromb Hemost | 1999 |
1 |
| 6 | 10446085 | Specific impairment of human platelet P2Y(AC) ADP receptor-mediated signaling by the antiplatelet drug clopidogrel. | Arterioscler Thromb Vasc Biol | 1999 Aug |
8 |
| 7 | 10506165 | Molecular mechanism of thromboxane A(2)-induced platelet aggregation. Essential role for p2t(ac) and alpha(2a) receptors. | J Biol Chem | 1999 Oct 8 |
3 |
| 8 | 10544922 | Role of intracellular signaling events in ADP-induced platelet aggregation. | Thromb Haemost | 1999 Oct |
4 |
| 9 | 10751543 | On the mechanism of plasmin-induced platelet aggregation. Implications of the dual role of granule ADP. | Biochem Pharmacol | 2000 Jun 1 |
2 |
| 10 | 10960076 | ADP is not an agonist at P2X(1) receptors: evidence for separate receptors stimulated by ATP and ADP on human platelets. | Br J Pharmacol | 2000 Sep |
2 |
| 11 | 11104774 | ADP is the cognate ligand for the orphan G protein-coupled receptor SP1999. | J Biol Chem | 2001 Mar 16 |
9 |
| 12 | 11215376 | [Aggregation of human blood platelets by remnant-like lipoprotein particles]. | Nihon Yakurigaku Zasshi | 2000 Nov |
1 |
| 13 | 11245644 | Ticlopidine pretreatment before coronary stenting is associated with sustained decrease in adverse cardiac events: data from the Evaluation of Platelet IIb/IIIa Inhibitor for Stenting (EPISTENT) Trial. | Circulation | 2001 Mar 13 |
1 |
| 14 | 11413167 | Molecular identification and characterization of the platelet ADP receptor targeted by thienopyridine antithrombotic drugs. | J Clin Invest | 2001 Jun |
1 |
| 15 | 11454254 | The P2Y12 receptor as a therapeutic target in cardiovascular disease. | Platelets | 2001 Jun |
6 |
| 16 | 11459636 | Novel tricyclic benzothiazolo[2,3-c]thiadiazine antagonists of the platelet ADP receptor (P2Y(12)). | Bioorg Med Chem Lett | 2001 Jul 23 |
2 |
| 17 | 11502873 | Molecular cloning of the platelet P2T(AC) ADP receptor: pharmacological comparison with another ADP receptor, the P2Y(1) receptor. | Mol Pharmacol | 2001 Sep |
8 |
| 18 | 11756171 | Adenosine diphosphate (ADP)-induced thromboxane A(2) generation in human platelets requires coordinated signaling through integrin alpha(IIb)beta(3) and ADP receptors. | Blood | 2002 Jan 1 |
4 |
| 19 | 11815620 | A Gi-dependent pathway is required for activation of the small GTPase Rap1B in human platelets. | J Biol Chem | 2002 Apr 5 |
1 |
| 20 | 11950711 | Role of ADP receptor P2Y(12) in platelet adhesion and thrombus formation in flowing blood. | Arterioscler Thromb Vasc Biol | 2002 Apr 1 |
3 |
| 21 | 12353080 | Inhibition of ADP-induced P-selectin expression and platelet-leukocyte conjugate formation by clopidogrel and the P2Y12 receptor antagonist AR-C69931MX but not aspirin. | Thromb Haemost | 2002 Sep |
2 |
| 22 | 12560222 | Inactivation of the human P2Y12 receptor by thiol reagents requires interaction with both extracellular cysteine residues, Cys17 and Cys270. | Blood | 2003 May 15 |
25 |
| 23 | 12578987 | Molecular bases of defective signal transduction in the platelet P2Y12 receptor of a patient with congenital bleeding. | Proc Natl Acad Sci U S A | 2003 Feb 18 |
8 |
| 24 | 12588350 | Effect of clopidogrel administration to healthy volunteers on platelet phosphorylation events triggered by ADP. | Br J Haematol | 2003 Feb |
1 |
| 25 | 12615691 | In vivo blockade of platelet ADP receptor P2Y12 reduces embolus and thrombus formation but not thrombus stability. | Arterioscler Thromb Vasc Biol | 2003 Mar 1 |
3 |
| 26 | 12806027 | P2 receptors and platelet activation. | ScientificWorldJournal | 2002 Feb 13 |
2 |
| 27 | 12812379 | The effect of a loading dose (300 mg) of clopidogrel on platelet function in patients with peripheral arterial disease. | Clin Appl Thromb Hemost | 2003 Apr |
1 |
| 28 | 12912815 | Adenosine diphosphate-induced platelet aggregation is associated with P2Y12 gene sequence variations in healthy subjects. | Circulation | 2003 Aug 26 |
2 |
| 29 | 12913786 | Scientific and therapeutic insights into the role of the platelet P2Y12 receptor in thrombosis. | Curr Opin Hematol | 2003 Sep |
6 |
| 30 | 14573771 | Purification and functional reconstitution of the human P2Y12 receptor. | Mol Pharmacol | 2003 Nov |
4 |
| 31 | 14597584 | Anticoagulants (thrombin inhibitors) and aspirin synergize with P2Y12 receptor antagonism in thrombosis. | Circulation | 2003 Nov 25 |
1 |
| 32 | 14610915 | ADP receptor antagonists as antiplatelet therapeutics. | Expert Opin Emerg Drugs | 2003 May |
6 |
| 33 | 14645014 | The plaque lipid lysophosphatidic acid stimulates platelet activation and platelet-monocyte aggregate formation in whole blood: involvement of P2Y1 and P2Y12 receptors. | Blood | 2004 Apr 1 |
4 |
| 34 | 14662702 | P2Y12 H2 haplotype is associated with peripheral arterial disease: a case-control study. | Circulation | 2003 Dec 16 |
2 |
| 35 | 14670370 | Inhibition of ADP-induced intracellular Ca2+ responses and platelet aggregation by the P2Y12 receptor antagonists AR-C69931MX and clopidogrel is enhanced by prostaglandin E1. | Cell Calcium | 2004 Jan |
3 |
| 36 | 14706855 | Costimulation of the Gi-coupled ADP receptor and the Gq-coupled TXA2 receptor is required for ERK2 activation in collagen-induced platelet aggregation. | FEBS Lett | 2004 Jan 2 |
4 |
| 37 | 14717977 | Gi-dependent and -independent mechanisms downstream of the P2Y12 ADP-receptor. | J Thromb Haemost | 2004 Jan |
4 |
| 38 | 15140134 | Different G protein-coupled signaling pathways are involved in alpha granule release from human platelets. | J Thromb Haemost | 2004 Jun |
2 |
| 39 | 15154604 | The effect of clopidogrel, aspirin and both antiplatelet drugs on platelet function in patients with peripheral arterial disease. | Platelets | 2004 Mar |
1 |
| 40 | 15187029 | Reciprocal cross-talk between P2Y1 and P2Y12 receptors at the level of calcium signaling in human platelets. | Blood | 2004 Sep 15 |
1 |
| 41 | 15203713 | Collagen-induced generation of platelet-derived microparticles in whole blood is dependent on ADP released from red blood cells and calcium ions. | Platelets | 2004 Jun |
3 |
| 42 | 15213852 | ADP secretion and subsequent P2Y12 receptor signalling play a crucial role in thrombin-induced ERK2 activation in human platelets. | Thromb Haemost | 2004 Jul |
5 |
| 43 | 15265806 | Synergistic action between inhibition of P2Y12/P2Y1 and P2Y12/thrombin in ADP- and thrombin-induced human platelet activation. | Br J Pharmacol | 2004 Aug |
2 |
| 44 | 15269827 | Pharmacokinetics of clopidogrel after administration of a high loading dose. | Thromb Haemost | 2004 Aug |
1 |
| 45 | 15291969 | P2 receptor mRNA expression profiles in human lymphocytes, monocytes and CD34+ stem and progenitor cells. | BMC Immunol | 2004 Aug 3 |
1 |
| 46 | 15308557 | ADP receptor P2Y12 is expressed in vascular smooth muscle cells and stimulates contraction in human blood vessels. | Arterioscler Thromb Vasc Biol | 2004 Oct |
3 |
| 47 | 15333577 | Platelet adhesion and signaling induced by the octapeptide primary binding sequence (KOGEOGPK) from type III collagen. | FASEB J | 2004 Sep |
1 |
| 48 | 15345752 | Induction of novel agonist selectivity for the ADP-activated P2Y1 receptor versus the ADP-activated P2Y12 and P2Y13 receptors by conformational constraint of an ADP analog. | J Pharmacol Exp Ther | 2004 Dec |
3 |
| 49 | 15481977 | Architecture of P2Y nucleotide receptors: structural comparison based on sequence analysis, mutagenesis, and homology modeling. | J Med Chem | 2004 Oct 21 |
1 |
| 50 | 15583724 | Variable extent of clopidogrel responsiveness in patients after coronary stenting. | Thromb Haemost | 2004 Dec |
2 |