Title : Role of ADP receptor P2Y(12) in platelet adhesion and thrombus formation in flowing blood.

Pub. Date : 2002 Apr 1

PMID : 11950711






3 Functional Relationships(s)
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1 Identical platelet surface coverage, aggregate size, and morphology were found when a P2Y(12) antagonist, N(6)-(2-methylthioethyl)-2-(3,3,3-trifluoropropylthio)-beta,gamma-dichloromethylene ATP (also known as AR-C69931 MX), was added to control blood. n(6)-(2-methylthioethyl)-2-(3,3,3-trifluoropropylthio)-beta,gamma-dichloromethylene atp purinergic receptor P2Y12 Homo sapiens
2 Identical platelet surface coverage, aggregate size, and morphology were found when a P2Y(12) antagonist, N(6)-(2-methylthioethyl)-2-(3,3,3-trifluoropropylthio)-beta,gamma-dichloromethylene ATP (also known as AR-C69931 MX), was added to control blood. Cangrelor tetrasodium purinergic receptor P2Y12 Homo sapiens
3 This suggested that P2Y(12) and P2Y(1) were both involved in platelet adhesion on immobilized fibrinogen, thereby revealing it as ADP dependent. Adenosine Diphosphate purinergic receptor P2Y12 Homo sapiens