Protein Name purinergic receptor P2Y12
Organism Homo sapiens
Gene ID 64805
Gene Symbol

P2RY12

UniProt Q9H244 (P2Y12_HUMAN), A8K7T1 (A8K7T1_HUMAN)
Relationships Total Number of functionally related compound(s) : 297
Total Number of Articles : 1289
Description

purinergic receptor P2Y12

Gene Summary

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]

synonyms
  • P2Y purinoceptor 12
  • ADP-glucose receptor
  • G-protein coupled receptor SP1999
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Properties