Title : Different G protein-coupled signaling pathways are involved in alpha granule release from human platelets.

Pub. Date : 2004 Jun

PMID : 15140134






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 ADP-induced P-selectin expression was inhibited both by MRS 2179 (a P2Y1 selective antagonist) and AR-C69931MX (a P2Y12 selective antagonist), suggesting a role for both Galpha(q) and Galpha(i) pathways in ADP-mediated alpha granule release. Adenosine Diphosphate purinergic receptor P2Y12 Homo sapiens
2 The P2Y12 receptor plays an important role in thromboxane A(2)-mediated alpha granule release, and furthermore activation of Galpha(12/13) and Galpha(q) signaling pathway can cause alpha granule release. thromboxane a purinergic receptor P2Y12 Homo sapiens