Pub. Date : 2004 Jun
PMID : 15140134
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | ADP-induced P-selectin expression was inhibited both by MRS 2179 (a P2Y1 selective antagonist) and AR-C69931MX (a P2Y12 selective antagonist), suggesting a role for both Galpha(q) and Galpha(i) pathways in ADP-mediated alpha granule release. | Adenosine Diphosphate | purinergic receptor P2Y12 | Homo sapiens |
2 | The P2Y12 receptor plays an important role in thromboxane A(2)-mediated alpha granule release, and furthermore activation of Galpha(12/13) and Galpha(q) signaling pathway can cause alpha granule release. | thromboxane a | purinergic receptor P2Y12 | Homo sapiens |