Pub. Date : 2003 Mar 1
PMID : 12615691
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | One of the receptors involved in ADP-induced platelet activation is the P2Y12 receptor, which is a target for antithrombotic drugs. | Adenosine Diphosphate | purinergic receptor P2Y12 | Homo sapiens |
| 2 | Anesthetized rabbits were treated with the selective P2Y12 antagonists AR-C69931 MX (3 microg x kg x min(-1) IV) or clopidogrel (25 mg/kg orally). | cangrelor | purinergic receptor P2Y12 | Homo sapiens |
| 3 | CONCLUSIONS: These findings demonstrate that ADP and its P2Y12 receptor are involved in thrombus growth and especially in the formation of emboli on the downstream side of the initial thrombus. | Adenosine Diphosphate | purinergic receptor P2Y12 | Homo sapiens |