Tyrosine

cyclin dependent kinase 1 ; Homo sapiens







201 Article(s)
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Pub. Year
#Total Relationships
51 18247328 Involvement of the role of Chk1 in lithium-induced G2/M phase cell cycle arrest in hepatocellular carcinoma cells. 2008 Jul 1 2
52 18479465 Phosphorylation of cyclin dependent kinase 4 on tyrosine 17 is mediated by Src family kinases. 2008 Jun 2
53 18817634 Discovery and characterization of a novel inhibitor of CDC25B, LGH00045. 2008 Oct 1
54 17095507 How tyrosine 15 phosphorylation inhibits the activity of cyclin-dependent kinase 2-cyclin A. 2007 Feb 2 2
55 17210576 Phosphatase type 2A-dependent and -independent pathways for ATR phosphorylation of Chk1. 2007 Mar 9 1
56 17412972 Murine gammaherpesvirus 68 ORF20 induces cell-cycle arrest in G2 by inhibiting the Cdc2-cyclin B complex. 2007 May 2
57 17475221 Quinolone analogue inhibits tubulin polymerization and induces apoptosis via Cdk1-involved signaling pathways. 2007 Jun 30 1
58 17619824 Cell growth inhibition, G2M cell cycle arrest, and apoptosis induced by the novel compound Alternol in human gastric carcinoma cell line MGC803. 2007 Dec 1
59 17636382 New alternative phosphorylation sites on the cyclin dependent kinase 1/cyclin a complex in p53-deficient human cells treated with etoposide: possible association with etoposide-induced apoptosis. 2007 Oct 4
60 17989878 Effects of tetrandrine on apoptosis and radiosensitivity of nasopharyngeal carcinoma cell line CNE. 2007 Nov 1
61 18225552 P53 enhances ascorbyl stearate-induced G2/M arrest of human ovarian cancer cells. 2007 Nov-Dec 1
62 16481012 Priming phosphorylation of Chk2 by polo-like kinase 3 (Plk3) mediates its full activation by ATM and a downstream checkpoint in response to DNA damage. 2006 Apr 11 1
63 16546994 Absolute quantification of multisite phosphorylation by selective reaction monitoring mass spectrometry: determination of inhibitory phosphorylation status of cyclin-dependent kinases. 2006 Jun 1
64 16614167 p53 suppression of arsenite-induced mitotic catastrophe is mediated by p21CIP1/WAF1. 2006 Jul 2
65 16619491 Rocaglaol induces apoptosis and cell cycle arrest in LNCaP cells. 2006 Mar-Apr 1
66 16783362 Regulation of mitotic entry by microcephalin and its overlap with ATR signalling. 2006 Jul 2
67 16807237 DNA damage-induced down-regulation of human Cdc25C and Cdc2 is mediated by cooperation between p53 and maintenance DNA (cytosine-5) methyltransferase 1. 2006 Aug 25 1
68 16840322 Role for Wee1 in inhibition of G2-to-M transition through the cooperation of distinct human papillomavirus type 1 E4 proteins. 2006 Aug 1
69 17013563 Unscheduled CDK1 activity in G1 phase of the cell cycle triggers apoptosis in X-irradiated lymphocytic leukemia cells. 2006 Nov 2
70 17172433 Gallic acid causes inactivating phosphorylation of cdc25A/cdc25C-cdc2 via ATM-Chk2 activation, leading to cell cycle arrest, and induces apoptosis in human prostate carcinoma DU145 cells. 2006 Dec 2
71 15576941 Measurement of Wee kinase activity. 2005 2
72 15582998 p14ARF induces G2 cell cycle arrest in p53- and p21-deficient cells by down-regulating p34cdc2 kinase activity. 2005 Feb 25 1
73 15615778 G2 damage checkpoints: what is the turn-on? 2005 Jan 1 1
74 15780175 Viral infections and cell cycle G2/M regulation. 2005 Mar 2
75 15940258 Diallyl trisulfide-induced G(2)-M phase cell cycle arrest in human prostate cancer cells is caused by reactive oxygen species-dependent destruction and hyperphosphorylation of Cdc 25 C. 2005 Sep 15 2
76 14767478 Cyclin A/Cdk2 complexes regulate activation of Cdk1 and Cdc25 phosphatases in human cells. 2004 Apr 22 3
77 14968113 Cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation. 2004 Apr 8 1
78 15126376 A novel synthetic inhibitor of CDC25 phosphatases: BN82002. 2004 May 1 1
79 15136770 S-phase inhibition of cell cycle progression by a novel class of pyridopyrimidine tyrosine kinase inhibitors. 2004 Jun 1
80 15208305 Activation of Ras-Ral pathway attenuates p53-independent DNA damage G2 checkpoint. 2004 Aug 27 2
81 12669309 Inhibition of proteasome-dependent degradation of Wee1 in G2-arrested Hep3B cells by TGF beta 1. 2003 Apr 2
82 12811820 Caffeine induces G2/M arrest and apoptosis via a novel p53-dependent pathway in NB4 promyelocytic leukemia cells. 2003 Aug 1
83 12894503 Inhibition of cisplatin-induced ATR activity and enhanced sensitivity to cisplatin. 2003 May-Jun 1
84 12915131 Ha-ras overexpression mediated cell apoptosis in the presence of 5-fluorouracil. 2003 Aug 15 1
85 12973835 ErbB2 overexpression in human breast carcinoma is correlated with p21Cip1 up-regulation and tyrosine-15 hyperphosphorylation of p34Cdc2: poor responsiveness to chemotherapy with cyclophoshamide methotrexate, and 5-fluorouracil is associated with Erb2 overexpression and with p21Cip1 overexpression. 2003 Sep 15 1
86 14681206 SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase. 2003 Dec 15 2
87 11782384 Abolishment of the Tyr-15 inhibitory phosphorylation site on cdc2 reduces the radiation-induced G(2) delay, revealing a potential checkpoint in early mitosis. 2002 Jan 1 5
88 11807090 The checkpoint protein Chfr is a ligase that ubiquitinates Plk1 and inhibits Cdc2 at the G2 to M transition. 2002 Jan 21 1
89 11839095 Wild-type TP53 inhibits G(2)-phase checkpoint abrogation and radiosensitization induced by PD0166285, a WEE1 kinase inhibitor. 2002 Mar 1
90 11841447 p53-mediated downregulation of Chk1 abrogates the DNA damage-induced G2M checkpoint in K562 cells, resulting in increased apoptosis. 2002 Feb 1
91 11896603 Cdc25C interacts with PCNA at G2/M transition. 2002 Mar 7 1
92 11952644 G2-phase radiation response in lymphoblastoid cell lines from Nijmegen breakage syndrome. 2002 Apr 1
93 12049736 Phosphorylation on tyrosine-15 of p34(Cdc2) by ErbB2 inhibits p34(Cdc2) activation and is involved in resistance to taxol-induced apoptosis. 2002 May 4
94 12222840 Suppression of Cdc2 dephosphorylation at the tyrosine 15 residue during nitrosourea-induced G2M phase arrest in glioblastoma cell lines. 2002 Aug 2
95 12384528 Enhanced sensitization to taxol-induced apoptosis by herceptin pretreatment in ErbB2-overexpressing breast cancer cells. 2002 Oct 15 4
96 12472573 Etoposide-mediated deregulation of the G2M checkpoint in myeloid leukaemic cell lines results in loss of cell survival. 2002 Dec 5
97 12658801 Failure to inactivate CDK activity is responsible for the enhanced apoptotic response in U937 cells mediated by silencing ATM gene. 2002 4
98 11098059 Altered regulation of cell cycle machinery involved in interleukin-1-induced G(1) and G(2) phase growth arrest of A375S2 human melanoma cells. 2001 Mar 2 6
99 11163155 DNA damage: Chk1 and Cdc25, more than meets the eye. 2001 Feb 2
100 11283255 S and G2 phase roles for Cdk2 revealed by inducible expression of a dominant-negative mutant in human cells. 2001 Apr 1