Title : Regulation of mitotic entry by microcephalin and its overlap with ATR signalling.

Pub. Date : 2006 Jul

PMID : 16783362






2 Functional Relationships(s)
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1 In contrast with ATR-Seckel syndrome cells, MCPH1-mutant cells have low levels of Tyr 15-phosphorylated Cdk1 (pY15-Cdk1) in S and G2 phases, which correlates with an elevated frequency of G2-like cells displaying premature chromosome condensation (PCC). Tyrosine cyclin dependent kinase 1 Homo sapiens
2 In contrast with ATR-Seckel syndrome cells, MCPH1-mutant cells have low levels of Tyr 15-phosphorylated Cdk1 (pY15-Cdk1) in S and G2 phases, which correlates with an elevated frequency of G2-like cells displaying premature chromosome condensation (PCC). Tyrosine cyclin dependent kinase 1 Homo sapiens