Title : p14ARF induces G2 cell cycle arrest in p53- and p21-deficient cells by down-regulating p34cdc2 kinase activity.

Pub. Date : 2005 Feb 25

PMID : 15582998






1 Functional Relationships(s)
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1 The p14(ARF)-induced depletion of p34(cdc2) was associated with impaired cdc25C phosphatase expression and a prominent shift to inhibitory Tyr-15-phosphorylation in G(2)-arrested cells lacking either p53, p21, or both. Tyrosine cyclin dependent kinase 1 Homo sapiens