Title : S-phase inhibition of cell cycle progression by a novel class of pyridopyrimidine tyrosine kinase inhibitors.

Pub. Date : 2004 Jun

PMID : 15136770






1 Functional Relationships(s)
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Protein Name
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1 Treatment of cells with the S-phase blocker PD179483 causes abnormal and persistent hyperactivation of Cdk2 and Cdc2 due to Tyr-15 dephosphorylation. Tyrosine cyclin dependent kinase 1 Homo sapiens