Title : Phosphorylation on tyrosine-15 of p34(Cdc2) by ErbB2 inhibits p34(Cdc2) activation and is involved in resistance to taxol-induced apoptosis.

Pub. Date : 2002 May

PMID : 12049736






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Phosphorylation on tyrosine-15 of p34(Cdc2) by ErbB2 inhibits p34(Cdc2) activation and is involved in resistance to taxol-induced apoptosis. Tyrosine cyclin dependent kinase 1 Homo sapiens
2 Phosphorylation on tyrosine-15 of p34(Cdc2) by ErbB2 inhibits p34(Cdc2) activation and is involved in resistance to taxol-induced apoptosis. Tyrosine cyclin dependent kinase 1 Homo sapiens
3 Here, we report that the inhibitory phosphorylation on Cdc2 tyrosine (Y)15 (Cdc2-Y15-p) is elevated in ErbB2-overexpressing breast cancer cells and primary tumors. Tyrosine cyclin dependent kinase 1 Homo sapiens
4 Here, we report that the inhibitory phosphorylation on Cdc2 tyrosine (Y)15 (Cdc2-Y15-p) is elevated in ErbB2-overexpressing breast cancer cells and primary tumors. Tyrosine cyclin dependent kinase 1 Homo sapiens