Dipeptides

cathepsin B ; Homo sapiens







21 Article(s)
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1 34953094 Engineering Enzyme-Cleavable Oligonucleotides by Automated Solid-Phase Incorporation of Cathepsin B Sensitive Dipeptide Linkers. 2022 Mar 21 2
2 32798638 Controlled loading of albumin-drug conjugates ex vivo for enhanced drug delivery and antitumor efficacy. 2020 Dec 10 1
3 31184188 Preparation of a Multiple-Targeting NIR-Based Fluorogenic Probe and Its Application for Selective Cancer Cell Imaging. 2019 Jun 21 1
4 29473076 Impact of cathepsin B-sensitive triggers and hydrophilic linkers on in vitro efficacy of novel site-specific antibody-drug conjugates. 2018 Mar 14 1
5 31156276 Improved Methodology for the Synthesis of a Cathepsin B Cleavable Dipeptide Linker, Widely Used in Antibody-Drug Conjugate Research. 2018 Oct 3 1
6 29123088 A water-soluble nucleolin aptamer-paclitaxel conjugate for tumor-specific targeting in ovarian cancer. 2017 Nov 9 2
7 23903896 Preclinical studies of targeted therapies for CD20-positive B lymphoid malignancies by Ofatumumab conjugated with auristatin. 2014 Feb 1
8 23712251 Toward very potent, non-covalent organophosphonate inhibitors of cathepsin C and related enzymes by 2-amino-1-hydroxy-alkanephosphonates dipeptides. 2013 Aug 1
9 24900316 Design, Synthesis, and Antitumor Activity of 4-Halocolchicines and Their Pro-drugs Activated by Cathepsin B. 2011 May 12 1
10 19131246 Development of dual-acting prodrugs for circumventing multidrug resistance. 2009 Feb 1 1
11 19199576 Development of protein-binding bifunctional linkers for a new generation of dual-acting prodrugs. 2009 Feb 1
12 11802791 S2' substrate specificity and the role of His110 and His111 in the exopeptidase activity of human cathepsin B. 2002 Feb 1 2
13 12121142 Cathepsin B-labile dipeptide linkers for lysosomal release of doxorubicin from internalizing immunoconjugates: model studies of enzymatic drug release and antigen-specific in vitro anticancer activity. 2002 Jul-Aug 1
14 10841792 Peptide and peptide mimetic inhibitors of antigen presentation by HLA-DR class II MHC molecules. Design, structure-activity relationships, and X-ray crystal structures. 2000 Jun 1 1
15 9873731 Cathepsin B-sensitive dipeptide prodrugs. 1. A model study of structural requirements for efficient release of doxorubicin. 1998 Dec 1 1
16 9873732 Cathepsin B-sensitive dipeptide prodrugs. 2. Models of anticancer drugs paclitaxel (Taxol), mitomycin C and doxorubicin. 1998 Dec 1 2
17 8754751 The combined action of two thyroidal proteases releases T4 from the dominant hormone-forming site of thyroglobulin. 1996 Aug 2
18 8230139 Peptide alpha-keto ester, alpha-keto amide, and alpha-keto acid inhibitors of calpains and other cysteine proteases. 1993 Oct 29 1
19 1797709 Synthesis of histidine-containing dipeptide affinity-labelling agents. Relative inactivation rates of cathepsins B and L. 1991 Oct 1
20 3318115 [Brain cathepsin as dipeptidylcarboxypeptidase transforming provasopressor, pro-opioid and model peptides]. 1987 Sep-Oct 2
21 666735 The specificity of cathepsin B. Hydrolysis of glucagon at the C-terminus by a peptidyldipeptidase mechanism. 1978 Jun 1 1