Title : Cathepsin B-sensitive dipeptide prodrugs. 2. Models of anticancer drugs paclitaxel (Taxol), mitomycin C and doxorubicin.

Pub. Date : 1998 Dec 1

PMID : 9873732






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Cathepsin B-sensitive dipeptide prodrugs. Dipeptides cathepsin B Homo sapiens
2 Substrates containing doxorubicin (DOX), paclitaxel (taxol), and mitomycin C (MMC) attached to the cathepsin B-sensitive dipeptide Phe-Lys via a self-immolative spacer were prepared as model compounds for internalizing anticancer immunoconjugates. Dipeptides cathepsin B Homo sapiens