Pub. Date : 2002 Feb 1
PMID : 11802791
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The ability of the lysosomal cysteine protease cathepsin B to function as a peptidyldipeptidase (removing C-terminal dipeptides) has been attributed to the presence of two histidine residues (His(110) and His(111)) present in the occluding loop, an extra peptide segment located in the primed side of the active-site cleft. | Dipeptides | cathepsin B | Homo sapiens |
2 | These studies showed that cathepsin B is optimized to act as an exopeptidase, cleaving dipeptides from protein substrates in a successive manner, because of its relaxed specificity in P2" and its other subsites. | Dipeptides | cathepsin B | Homo sapiens |