Title : [Brain cathepsin as dipeptidylcarboxypeptidase transforming provasopressor, pro-opioid and model peptides].

Pub. Date : 1987 Sep-Oct

PMID : 3318115

2 Functional Relationships(s)
Compound Name
Protein Name
1 Recently the factors, contributing to dipeptidyl carboxypeptidase properties of brain cathepsin B, were identified: I. occupation of the enzyme S3 subsite, 2. free C-terminal group of the substrate, 3. specific interaction between the split off dipeptide and the enzyme active site. Dipeptides cathepsin B Homo sapiens
2 Cathepsin B split off the C-terminal dipeptide in synthetic substrates Leu-Trp-Met-Arg-Phe-Ala and Trp-Met-Arg-Phe-Ala but not in Met-Arg-Phe-Ala. Dipeptides cathepsin B Homo sapiens