Title : Toward very potent, non-covalent organophosphonate inhibitors of cathepsin C and related enzymes by 2-amino-1-hydroxy-alkanephosphonates dipeptides.

Pub. Date : 2013 Aug

PMID : 23712251






1 Functional Relationships(s)
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1 These dipeptide mimetics appear also to be potent inhibitors of other cysteine proteases such as papain, cathepsin B and cathepsin K, thus providing new leading structures for these medicinally important enzymes. Dipeptides cathepsin B Homo sapiens