| 1 |
33562083 | A Novel, LAT/Lck Double Deficient T Cell Subline J.CaM1.7 for Combined Analysis of Early TCR Signaling. | 2021 Feb 6 |
1 |
| 2 |
33791292 | How the Discovery of the CD4/CD8-p56lck Complexes Changed Immunology and Immunotherapy. | 2021 |
1 |
| 3 |
34149695 | Identification and Characterization of the Amphioxus Lck and Its Associated Tyrosine Phosphorylation-Dependent Inhibitory LRR Receptor. | 2021 |
4 |
| 4 |
34414199 | Downregulation of CD45 Signaling in COVID-19 Patients Is Reversed by C24D, a Novel CD45 Targeting Peptide. | 2021 |
1 |
| 5 |
35186948 | TCR-Induced Tyrosine Phosphorylation at Tyr270 of SUMO Protease SENP1 by Lck Modulates SENP1 Enzyme Activity and Specificity. | 2021 |
1 |
| 6 |
32446033 | Engagement of CD45 alters early signaling events in human T cells co-stimulated through TCR + CD28. | 2020 Jul |
1 |
| 7 |
33225946 | Tyrosine 192 within the SH2 domain of the Src-protein tyrosine kinase p56Lck regulates T-cell activation independently of Lck/CD45 interactions. | 2020 Nov 23 |
3 |
| 8 |
33374422 | The Activity and Stability of p56Lck and TCR Signaling Do Not Depend on the Co-Chaperone Cdc37. | 2020 Dec 24 |
1 |
| 9 |
31679194 | TAOK3, a Regulator of LCK-SHP-1 Crosstalk during TCR Signaling. | 2019 |
1 |
| 10 |
29410624 | CP-25 Attenuates the Activation of CD4+ T Cells Stimulated with Immunoglobulin D in Human. | 2018 |
1 |
| 11 |
29903769 | YAP Tyrosine Phosphorylation and Nuclear Localization in Cholangiocarcinoma Cells Are Regulated by LCK and Independent of LATS Activity. | 2018 Oct |
1 |
| 12 |
30197180 | Computational Model of Chimeric Antigen Receptors Explains Site-Specific Phosphorylation Kinetics. | 2018 Sep 18 |
2 |
| 13 |
30282749 | HIV-1 Nef Hijacks Lck and Rac1 Endosomal Traffic To Dually Modulate Signaling-Mediated and Actin Cytoskeleton-Mediated T Cell Functions. | 2018 Nov 1 |
2 |
| 14 |
30372858 | Exploration of the therapeutic aspects of Lck: A kinase target in inflammatory mediated pathological conditions. | 2018 Dec |
2 |
| 15 |
28096507 | De novo phosphorylation and conformational opening of the tyrosine kinase Lck act in concert to initiate T cell receptor signaling. | 2017 Jan 17 |
5 |
| 16 |
28235866 | Rab11-FIP3 Regulation of Lck Endosomal Traffic Controls TCR Signal Transduction. | 2017 Apr 1 |
1 |
| 17 |
27014263 | Distinct Mechanisms Regulate Lck Spatial Organization in Activated T Cells. | 2016 |
5 |
| 18 |
27441653 | WASH has a critical role in NK cell cytotoxicity through Lck-mediated phosphorylation. | 2016 Jul 21 |
1 |
| 19 |
25316710 | SRC homology 2 domain-containing leukocyte phosphoprotein of 76 kDa (SLP-76) N-terminal tyrosine residues regulate a dynamic signaling equilibrium involving feedback of proximal T-cell receptor (TCR) signaling. | 2015 Jan |
1 |
| 20 |
25420722 | The pool of preactivated Lck in the initiation of T-cell signaling: a critical re-evaluation of the Lck standby model. | 2015 Apr |
1 |
| 21 |
25990959 | The catalytic activity of the kinase ZAP-70 mediates basal signaling and negative feedback of the T cell receptor pathway. | 2015 May 19 |
3 |
| 22 |
26043137 | Vav1 Regulates T-Cell Activation through a Feedback Mechanism and Crosstalk between the T-Cell Receptor and CD28. | 2015 Jul 2 |
1 |
| 23 |
26310847 | Novel roles for LIX1L in promoting cancer cell proliferation through ROS1-mediated LIX1L phosphorylation. | 2015 Aug 27 |
1 |
| 24 |
26421924 | Conserved Motifs within Hepatitis C Virus Envelope (E2) RNA and Protein Independently Inhibit T Cell Activation. | 2015 Sep |
1 |
| 25 |
24231767 | GM1 controlled lateral segregation of tyrosine kinase Lck predispose T-cells to cell-derived galectin-1-induced apoptosis. | 2014 Feb |
1 |
| 26 |
24405902 | Downregulation of inhibitory SRC homology 2 domain-containing phosphatase-1 (SHP-1) leads to recovery of T cell responses in elderly. | 2014 Jan 9 |
2 |
| 27 |
24524084 | SEA antagonizes the imatinib-meditated inhibitory effects on T cell activation via the TCR signaling pathway. | 2014 |
1 |
| 28 |
25128530 | Phosphatase CD45 both positively and negatively regulates T cell receptor phosphorylation in reconstituted membrane protein clusters. | 2014 Oct 10 |
3 |
| 29 |
25492967 | The kinase Itk and the adaptor TSAd change the specificity of the kinase Lck in T cells by promoting the phosphorylation of Tyr192. | 2014 Dec 9 |
6 |
| 30 |
23427257 | Differential polarization of C-terminal Src kinase between naive and antigen-experienced CD8+ T cells. | 2013 Apr 1 |
1 |
| 31 |
23530057 | Structural basis for activation of ZAP-70 by phosphorylation of the SH2-kinase linker. | 2013 Jun |
1 |
| 32 |
23874979 | ERK positive feedback regulates a widespread network of tyrosine phosphorylation sites across canonical T cell signaling and actin cytoskeletal proteins in Jurkat T cells. | 2013 |
1 |
| 33 |
23880762 | Mitochondria-derived hydrogen peroxide selectively enhances T cell receptor-initiated signal transduction. | 2013 Sep 6 |
1 |
| 34 |
23946459 | Role of herpes simplex virus VP11/12 tyrosine-based motifs in binding and activation of the Src family kinase Lck and recruitment of p85, Grb2, and Shc. | 2013 Oct |
1 |
| 35 |
24155921 | Phosphorylation of FOXP3 by LCK downregulates MMP9 expression and represses cell invasion. | 2013 |
2 |
| 36 |
22281390 | A specific type of membrane microdomains is involved in the maintenance and translocation of kinase active Lck to lipid rafts. | 2012 Feb 29 |
1 |
| 37 |
22382333 | Effects of halogenation on tyrosine phosphorylation and peptide binding to the SRC homology 2 domain of lymphocyte-specific protein tyrosine kinase. | 2012 |
2 |
| 38 |
22537350 | Functional requirements for inhibitory signal transmission by the immunomodulatory receptor CD300a. | 2012 Apr 26 |
1 |
| 39 |
22674786 | TCR-induced T cell activation leads to simultaneous phosphorylation at Y505 and Y394 of p56(lck) residues. | 2012 Sep |
1 |
| 40 |
22723799 | How does the kinase Lck phosphorylate the T cell receptor? Spatial organization as a regulatory mechanism. | 2012 |
1 |
| 41 |
21149606 | Cutting edge: NKp80 uses an atypical hemi-ITAM to trigger NK cytotoxicity. | 2011 Jan 15 |
1 |
| 42 |
21463338 | Ethanol inhibits lipid raft-mediated TCR signaling and IL-2 expression: potential mechanism of alcohol-induced immune suppression. | 2011 Aug |
1 |
| 43 |
22084078 | Basic residues in the T-cell receptor ζ cytoplasmic domain mediate membrane association and modulate signaling. | 2011 Nov 29 |
2 |
| 44 |
20028775 | The T cell receptor-mediated phosphorylation of Pyk2 tyrosines 402 and 580 occurs via a distinct mechanism than other receptor systems. | 2010 Apr |
1 |
| 45 |
20194498 | T cell signal regulation by the actin cytoskeleton. | 2010 May 7 |
1 |
| 46 |
20208138 | Pre T-cell receptor alpha (pTalpha) expression patterns and functional analysis in human T-cell lymphoblastic leukemia. | 2010 |
1 |
| 47 |
20305788 | T cell specific adapter protein (TSAd) interacts with Tec kinase ITK to promote CXCL12 induced migration of human and murine T cells. | 2010 Mar 18 |
1 |
| 48 |
20346773 | CD45-Csk phosphatase-kinase titration uncouples basal and inducible T cell receptor signaling during thymic development. | 2010 Mar 26 |
1 |
| 49 |
20538612 | Autoimmune-associated PTPN22 R620W variation reduces phosphorylation of lymphoid phosphatase on an inhibitory tyrosine residue. | 2010 Aug 20 |
1 |
| 50 |
20728542 | Cloning, characterization, and expression pattern of Atlantic halibut (Hippoglossus hippoglossus L.) CD4-2, Lck, and ZAP-70. | 2010 Dec |
2 |