Title : Cloning, characterization, and expression pattern of Atlantic halibut (Hippoglossus hippoglossus L.) CD4-2, Lck, and ZAP-70.

Pub. Date : 2010 Dec

PMID : 20728542






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Lck phosphorylates tyrosine residues within the CD3 chains, providing docking sites for a 70 kDa zeta-associated-protein (ZAP-70), a tyrosine protein kinase important for T-cell signaling. Tyrosine LCK proto-oncogene, Src family tyrosine kinase Homo sapiens
2 Tyrosine residues important in Lck activation were conserved within the SH1 and COOH-domain. Tyrosine LCK proto-oncogene, Src family tyrosine kinase Homo sapiens