| 51 |
21152094 | T cell receptor signal initiation induced by low-grade stimulation requires the cooperation of LAT in human T cells. | 2010 Nov 30 |
2 |
| 52 |
19059208 | Inhibition of NF-kappaB signaling via tyrosine phosphorylation of Ymer. | 2009 Jan 23 |
1 |
| 53 |
19168706 | T-cell receptor signaling is mediated by transient Lck activity, which is inhibited by inorganic mercury. | 2009 Jun |
3 |
| 54 |
19192391 | PKD2 interacts with Lck and regulates NFAT activity in T cells. | 2009 Jan 31 |
2 |
| 55 |
19201754 | T cell receptor-dependent tyrosine phosphorylation of beta2-chimaerin modulates its Rac-GAP function in T cells. | 2009 Apr 24 |
1 |
| 56 |
19776125 | Herpes simplex virus requires VP11/12 to induce phosphorylation of the activation loop tyrosine (Y394) of the Src family kinase Lck in T lymphocytes. | 2009 Dec |
4 |
| 57 |
19858202 | Cannabinoid receptor type 1- and 2-mediated increase in cyclic AMP inhibits T cell receptor-triggered signaling. | 2009 Dec 18 |
3 |
| 58 |
18253061 | Tyrosine phosphorylation of netrin receptors in netrin-1 signaling. | 2008 |
2 |
| 59 |
18424699 | Lck-dependent tyrosine phosphorylation of diacylglycerol kinase alpha regulates its membrane association in T cells. | 2008 May 1 |
1 |
| 60 |
18541536 | Modulation of Lck function through multisite docking to T cell-specific adapter protein. | 2008 Aug 8 |
16 |
| 61 |
18548611 | Intracellular Phospho-Flow cytometry reveals novel insights into TCR proximal signaling events. A comparison with Western blot. | 2008 Sep |
2 |
| 62 |
18976935 | Tyrosine-phosphorylation-dependent translocation of the SLAT protein to the immunological synapse is required for NFAT transcription factor activation. | 2008 Nov 14 |
2 |
| 63 |
17726154 | Modulation of CD1d-restricted NKT cell responses by CD4. | 2007 Dec |
1 |
| 64 |
17897955 | A weak Lck tail bite is necessary for Lck function in T cell antigen receptor signaling. | 2007 Dec 7 |
1 |
| 65 |
17947241 | Clustering of membrane raft proteins by the actin cytoskeleton. | 2007 Dec 14 |
1 |
| 66 |
16257509 | Lck couples Shc to TCR signaling. | 2006 Aug |
1 |
| 67 |
16461343 | Identification of substrates of human protein-tyrosine phosphatase PTPN22. | 2006 Apr 21 |
5 |
| 68 |
17005671 | Growth transformation of human T cells by herpesvirus saimiri requires multiple Tip-Lck interaction motifs. | 2006 Oct |
2 |
| 69 |
17050525 | Vav1 acidic region tyrosine 174 is required for the formation of T cell receptor-induced microclusters and is essential in T cell development and activation. | 2006 Dec 15 |
3 |
| 70 |
17100647 | Expression of human tyrosine kinase, Lck, in yeast Saccharomyces cerevisiae: growth suppression and strategy for inhibitor screening. | 2006 |
3 |
| 71 |
15671290 | The influence of SRC-family tyrosine kinases on Na,K-ATPase activity in lens epithelium. | 2005 Feb |
2 |
| 72 |
15743830 | Activation of hematopoietic progenitor kinase 1 involves relocation, autophosphorylation, and transphosphorylation by protein kinase D1. | 2005 Mar |
1 |
| 73 |
15827961 | The C terminus of T cell-specific adapter protein (TSAd) is necessary for TSAd-mediated inhibition of Lck activity. | 2005 May |
1 |
| 74 |
15892963 | Nef enhances c-Cbl phosphorylation in HIV-infected CD4+ T lymphocytes. | 2005 Jun 5 |
1 |
| 75 |
16087662 | The Epstein-Barr virus protein, latent membrane protein 2A, co-opts tyrosine kinases used by the T cell receptor. | 2005 Oct 7 |
2 |
| 76 |
16143319 | Silencing OCILRP2 leads to intrinsic defects in T cells in response to antigenic stimulation. | 2005 May |
1 |
| 77 |
16154907 | Regulation of expression and function of Lck tyrosine kinase by high cell density. | 2005 Jul-Aug |
2 |
| 78 |
16339550 | T cell activation-induced CrkII binding to the Zap70 protein tyrosine kinase is mediated by Lck-dependent phosphorylation of Zap70 tyrosine 315. | 2005 Dec 15 |
1 |
| 79 |
14699120 | Tyrosine kinase, p56lck-induced cell motility, and urokinase-type plasminogen activator secretion involve activation of epidermal growth factor receptor/extracellular signal regulated kinase pathways. | 2004 Mar 12 |
8 |
| 80 |
14730347 | Frameshift mutation in the Dok1 gene in chronic lymphocytic leukemia. | 2004 Mar 25 |
1 |
| 81 |
14757365 | Lysophosphatidylcholine is a regulator of tyrosine kinase activity and intracellular Ca(2+) level in Jurkat T cell line. | 2004 Jan 30 |
1 |
| 82 |
15050291 | Tyrosine phosphorylation-dependent activation of NFkappaB is compromised in T cells from the elderly. | 2004 Apr |
2 |
| 83 |
15059847 | T-cell receptor-induced phosphorylation of the zeta chain is efficiently promoted by ZAP-70 but not Syk. | 2004 Aug 1 |
1 |
| 84 |
15169900 | Modulation of T-cell receptor signal transduction by herpesvirus signaling adaptor protein. | 2004 Jun |
2 |
| 85 |
15214778 | Identification of non-phosphate-containing small molecular weight inhibitors of the tyrosine kinase p56 Lck SH2 domain via in silico screening against the pY + 3 binding site. | 2004 Jul 1 |
1 |
| 86 |
15363460 | In silico activation of Src tyrosine kinase reveals the molecular basis for intramolecular autophosphorylation. | 2004 Oct |
1 |
| 87 |
15471856 | Misfolding of major histocompatibility complex class I molecules in activated T cells allows cis-interactions with receptors and signaling molecules and is associated with tyrosine phosphorylation. | 2004 Dec 17 |
1 |
| 88 |
15554922 | Epitope-specific crosslinking of CD45 down-regulates membrane-associated tyrosine phosphatase activity and triggers early signalling events in human activated T cells. | 2004 Dec |
1 |
| 89 |
15566962 | Phosphorylation of actin-binding protein (ABP-280; filamin) by tyrosine kinase p56lck modulates actin filament cross-linking. | 2004 |
1 |
| 90 |
12496963 | CD45 ectodomain controls interaction with GEMs and Lck activity for optimal TCR signaling. | 2003 Feb |
1 |
| 91 |
12570875 | Selective interaction of LAT (linker of activated T cells) with the open-active form of Lck in lipid rafts reveals a new mechanism for the regulation of Lck in T cells. | 2003 May 1 |
5 |
| 92 |
12589038 | Integrin-mediated tyrosine phosphorylation of Shc in T cells is regulated by protein kinase C-dependent phosphorylations of Lck. | 2003 Feb |
1 |
| 93 |
12600746 | The Polycomb-group protein ENX-2 interacts with ZAP-70. | 2003 Mar 3 |
1 |
| 94 |
12755691 | Investigation of the kinetics and order of tyrosine phosphorylation in the T-cell receptor zeta chain by the protein tyrosine kinase Lck. | 2003 Jun |
6 |
| 95 |
12794125 | A model for antigen-specific T-cell anergy: displacement of CD4-p56(lck) signalosome from the lipid rafts by a soluble, dimeric peptide-MHC class II chimera. | 2003 Jun 15 |
1 |
| 96 |
12842872 | Itk phosphorylation sites are required for functional activity in primary T cells. | 2003 Sep 26 |
1 |
| 97 |
12919032 | Synthesis of a new conformation-constrained L-tyrosine analogue as a potential scaffold for SH2 domain ligands. | 2003 Aug 22 |
1 |
| 98 |
12922168 | The noncatalytic domains of Lck regulate its dephosphorylation by CD45. | 2003 Aug 21 |
10 |
| 99 |
12928397 | Functional requirements for interactions between CD84 and Src homology 2 domain-containing proteins and their contribution to human T cell activation. | 2003 Sep 1 |
1 |
| 100 |
14523017 | CD38 signaling in T cells is initiated within a subset of membrane rafts containing Lck and the CD3-zeta subunit of the T cell antigen receptor. | 2003 Dec 12 |
1 |