Title : A Novel, LAT/Lck Double Deficient T Cell Subline J.CaM1.7 for Combined Analysis of Early TCR Signaling.

Pub. Date : 2021 Feb 6

PMID : 33562083






1 Functional Relationships(s)
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Protein Name
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1 Proper TCR signaling requires the sequential activities of Lck and ZAP-70 kinases, which result in the phosphorylation of tyrosine residues located in the CD3 ITAMs and the LAT adaptor, respectively. Tyrosine LCK proto-oncogene, Src family tyrosine kinase Homo sapiens