Title : Disruption of the Y-box binding protein-1 results in suppression of the epidermal growth factor receptor and HER-2.

Pub. Date : 2006 May 1

PMID : 16651443






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 We reasoned that the underlying cause for growth attenuation by YB-1(Ser(102)) is through the regulation of EGFR and/or HER-2. Serine epidermal growth factor receptor Homo sapiens
2 In conclusion, YB-1(Ser(102)) is a point of molecular vulnerability for maintaining the expression of EGFR and HER-2. Serine epidermal growth factor receptor Homo sapiens