Title : Increased oncogenic potential of ErbB is associated with the loss of a COOH-terminal domain serine phosphorylation site.

Pub. Date : 1992 Apr 25

PMID : 1349014






2 Functional Relationships(s)
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1 Increased oncogenic potential of ErbB is associated with the loss of a COOH-terminal domain serine phosphorylation site. Serine epidermal growth factor receptor Homo sapiens
2 Here we show that the mutation of erbB at this negative regulatory serine phosphorylation site causes fibroblast transformation in vitro and is associated with an increased oncogenic potential in vivo. Serine epidermal growth factor receptor Homo sapiens