Title : GM3 directly inhibits tyrosine phosphorylation and de-N-acetyl-GM3 directly enhances serine phosphorylation of epidermal growth factor receptor, independently of receptor-receptor interaction.

Pub. Date : 1994 Jan 21

PMID : 7507488






1 Functional Relationships(s)
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1 Findings iii and iv suggest that deNAcGM3 strongly promotes serine phosphorylation (in addition to Tyr phosphorylation) of EGF-R and may function as a second messenger in the process of cell growth stimulation. Serine epidermal growth factor receptor Homo sapiens