Tamoxifen

epidermal growth factor receptor ; Homo sapiens







120 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
51 20446926 (-)-Epigallocatechin-3-gallate down-regulates EGFR, MMP-2, MMP-9 and EMMPRIN and inhibits the invasion of MCF-7 tamoxifen-resistant cells. 2011 Apr 2
52 21273576 Measuring IGF-1, ER-α and EGFR expression can predict tamoxifen-resistance in ER-positive breast cancer. 2011 Jan 4
53 22042792 Dual IGF-1R/InsR inhibitor BMS-754807 synergizes with hormonal agents in treatment of estrogen-dependent breast cancer. 2011 Dec 15 1
54 19288272 Growth of hormone-dependent MCF-7 breast cancer cells is promoted by constitutive caveolin-1 whose expression is lost in an EGF-R-mediated manner during development of tamoxifen resistance. 2010 Feb 1
55 19739079 The effects of gefitinib in tamoxifen-resistant and hormone-insensitive breast cancer: a phase II study. 2010 Apr 15 3
56 19911269 Role of GPR30 in the mechanisms of tamoxifen resistance in breast cancer MCF-7 cells. 2010 Aug 1
57 20005069 Combined tamoxifen and gefitinib in non-small cell lung cancer shows antiproliferative effects. 2010 Feb 1
58 20847831 Lapatinib in the Treatment of Hormone Receptor-Positive/ErbB2-Positive Breast Cancer. 2010 1
59 20944147 The Wilms' tumor suppressor WT1 regulates expression of members of the epidermal growth factor receptor (EGFR) and estrogen receptor in acquired tamoxifen resistance. 2010 Sep 3
60 19138696 Estrogen signals via an extra-nuclear pathway involving IGF-1R and EGFR in tamoxifen-sensitive and -resistant breast cancer cells. 2009 Jul 2
61 19285025 AIB1 is required for the acquisition of epithelial growth factor receptor-mediated tamoxifen resistance in breast cancer cells. 2009 Mar 13 4
62 19749156 G protein-coupled receptor 30 expression is up-regulated by EGF and TGF alpha in estrogen receptor alpha-positive cancer cells. 2009 Nov 4
63 19923318 Emerging treatment combinations: integrating therapy into clinical practice. 2009 Dec 1 1
64 17636398 Epidermal growth factor receptor (EGFR) and the estrogen receptor modulator amplified in breast cancer (AIB1) for predicting clinical outcome after adjuvant tamoxifen in breast cancer. 2008 May 3
65 17902048 Insulin receptor substrate-1 involvement in epidermal growth factor receptor and insulin-like growth factor receptor signalling: implication for Gefitinib ('Iressa') response and resistance. 2008 Sep 3
66 18245484 Tamoxifen resistance in breast tumors is driven by growth factor receptor signaling with repression of classic estrogen receptor genomic function. 2008 Feb 1 5
67 18550772 Signal transducer and activator of transcription 5b, c-Src, and epidermal growth factor receptor signaling play integral roles in estrogen-stimulated proliferation of estrogen receptor-positive breast cancer cells. 2008 Aug 1
68 21048911 Limitations in Adjuvant Breast Cancer Therapy: The Predictive Potential of Pharmacogenetics and Pharmacogenomics. 2008 1
69 17013895 Novel combination therapy against metastatic and androgen-independent prostate cancer by using gefitinib, tamoxifen and etoposide. 2007 Jan 1 2
70 17234721 Soy phytochemicals synergistically enhance the preventive effect of tamoxifen on the growth of estrogen-dependent human breast carcinoma in mice. 2007 Jun 1
71 17283173 Long-term treatment with tamoxifen facilitates translocation of estrogen receptor alpha out of the nucleus and enhances its interaction with EGFR in MCF-7 breast cancer cells. 2007 Feb 1 2
72 17295235 Genistein sensitizes inhibitory effect of tamoxifen on the growth of estrogen receptor-positive and HER2-overexpressing human breast cancer cells. 2007 Jul 1
73 17332282 Amplified in breast cancer 1 in human epidermal growth factor receptor - positive tumors of tamoxifen-treated breast cancer patients. 2007 Mar 1 1
74 17355262 Critical role of estrogen receptor on anoikis and invasion of squamous cell carcinoma. 2007 May 1
75 17363451 Tamoxifen-induced rapid death of MCF-7 breast cancer cells is mediated via extracellularly signal-regulated kinase signaling and can be abrogated by estrogen. 2007 Jun 6
76 17634479 Quantitative measurement of epidermal growth factor receptor is a negative predictive factor for tamoxifen response in hormone receptor positive premenopausal breast cancer. 2007 Jul 20 8
77 17912634 Letrozole in the neoadjuvant setting: the P024 trial. 2007 1
78 18396622 [Correlation of Her-2 overexpression with endocrine status and response to tamoxifen treatment in patients with breast cancer]. 2007 Dec 11 1
79 16080193 Tamoxifen resistance in MCF7 cells promotes EMT-like behaviour and involves modulation of beta-catenin phosphorylation. 2006 Jan 15 1
80 16261397 Bidirectional cross talk between ERalpha and EGFR signalling pathways regulates tamoxifen-resistant growth. 2006 Mar 3
81 16333527 Elevated Src activity promotes cellular invasion and motility in tamoxifen resistant breast cancer cells. 2006 Jun 2
82 16455819 Activation function-1 domain of estrogen receptor regulates the agonistic and antagonistic actions of tamoxifen. 2006 May 2
83 16467116 Novel mechanisms of resistance to endocrine therapy: genomic and nongenomic considerations. 2006 Feb 1 1
84 16497822 Benefit from adjuvant tamoxifen therapy in primary breast cancer patients according oestrogen receptor, progesterone receptor, EGF receptor and HER2 status. 2006 May 1
85 16831274 [Involvement of epidermal growth factor receptor signaling pathway in tamoxifen resistance of MCF-7 cells]. 2006 Jul 4
86 16849545 Physical and functional interactions between Cas and c-Src induce tamoxifen resistance of breast cancer cells through pathways involving epidermal growth factor receptor and signal transducer and activator of transcription 5b. 2006 Jul 15 3
87 17048231 Serum epidermal growth factor receptor/HER-2 predicts poor survival in patients with metastatic breast cancer. 2006 Nov 15 1
88 17259562 Inductive mechanisms limiting response to anti-epidermal growth factor receptor therapy. 2006 Dec 3
89 15665275 The dual ErbB1/ErbB2 inhibitor, lapatinib (GW572016), cooperates with tamoxifen to inhibit both cell proliferation- and estrogen-dependent gene expression in antiestrogen-resistant breast cancer. 2005 Jan 1 4
90 15970523 Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in breast cancer: current status and future development. 2005 Sep 1 1
91 16000581 Can molecular markers predict when to implement treatment with aromatase inhibitors in invasive breast cancer? 2005 Jul 1 5
92 16037379 Insulin-like growth factor-I receptor signaling in tamoxifen-resistant breast cancer: a supporting role to the epidermal growth factor receptor. 2005 Nov 4
93 16113090 Overview of tyrosine kinase inhibitors in clinical breast cancer. 2005 Jul 2
94 16113104 Epidermal growth factor receptor/HER2/insulin-like growth factor receptor signalling and oestrogen receptor activity in clinical breast cancer. 2005 Jul 2
95 16145046 Estrogen receptor-positive, progesterone receptor-negative breast cancer: association with growth factor receptor expression and tamoxifen resistance. 2005 Sep 7 4
96 16202921 Analysis of estrogen agonism and antagonism of tamoxifen, raloxifene, and ICI182780 in endometrial cancer cells: a putative role for the epidermal growth factor receptor ligand amphiregulin. 2005 Oct 2
97 16273359 Advanced concepts in estrogen receptor biology and breast cancer endocrine resistance: implicated role of growth factor signaling and estrogen receptor coregulators. 2005 Nov 1
98 15015704 Importance of correlative science in advancing hormonal therapy and a new clinical paradigm for neoadjuvant therapy. 2004 Jan 1
99 15199112 Mechanisms of tamoxifen resistance: increased estrogen receptor-HER2/neu cross-talk in ER/HER2-positive breast cancer. 2004 Jun 16 1
100 15355892 HER-2 amplification, HER-1 expression, and tamoxifen response in estrogen receptor-positive metastatic breast cancer: a southwest oncology group study. 2004 Sep 1 2