Pub. Date : 2006 Dec
PMID : 17259562
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Here, we describe both non-genomic and genomic mechanisms of resistance to the selective EGFR tyrosine kinase inhibitor gefitinib (IRESSA), which we have identified initially in an EGFR-positive tamoxifen-resistant MCF-7 breast cancer cell line, but more recently in other EGFR-positive cancer types. | Tamoxifen | epidermal growth factor receptor | Homo sapiens |
2 | Here, we describe both non-genomic and genomic mechanisms of resistance to the selective EGFR tyrosine kinase inhibitor gefitinib (IRESSA), which we have identified initially in an EGFR-positive tamoxifen-resistant MCF-7 breast cancer cell line, but more recently in other EGFR-positive cancer types. | Tamoxifen | epidermal growth factor receptor | Homo sapiens |
3 | Here, we describe both non-genomic and genomic mechanisms of resistance to the selective EGFR tyrosine kinase inhibitor gefitinib (IRESSA), which we have identified initially in an EGFR-positive tamoxifen-resistant MCF-7 breast cancer cell line, but more recently in other EGFR-positive cancer types. | Tamoxifen | epidermal growth factor receptor | Homo sapiens |