Title : Overview of tyrosine kinase inhibitors in clinical breast cancer.

Pub. Date : 2005 Jul

PMID : 16113090






2 Functional Relationships(s)
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1 Studies of cell models and profiling of clinical breast cancer material to reveal the mechanisms of resistance to anti-oestrogen therapy, and to tamoxifen in particular, have reported that this phenomenon can be associated with increased expression and signalling through erbB Type 1 growth factor receptors, notably the epidermal growth factor receptor (EGFR) and HER2. Tamoxifen epidermal growth factor receptor Homo sapiens
2 Studies of cell models and profiling of clinical breast cancer material to reveal the mechanisms of resistance to anti-oestrogen therapy, and to tamoxifen in particular, have reported that this phenomenon can be associated with increased expression and signalling through erbB Type 1 growth factor receptors, notably the epidermal growth factor receptor (EGFR) and HER2. Tamoxifen epidermal growth factor receptor Homo sapiens