Pub. Date : 2011 Jan
PMID : 21273576
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Measuring IGF-1, ER-alpha and EGFR expression can predict tamoxifen-resistance in ER-positive breast cancer. | Tamoxifen | epidermal growth factor receptor | Homo sapiens |
| 2 | In vitro studies have suggested that tamoxifen resistance may be due to altered expression and downstream signalling of insulin-like growth factor-1 (IGF-1) receptor (IGF-1l), oestrogen receptor-alpha (ERalpha), epidermal growth factor receptor (EGFR) and HER-2. | Tamoxifen | epidermal growth factor receptor | Homo sapiens |
| 3 | In vitro studies have suggested that tamoxifen resistance may be due to altered expression and downstream signalling of insulin-like growth factor-1 (IGF-1) receptor (IGF-1l), oestrogen receptor-alpha (ERalpha), epidermal growth factor receptor (EGFR) and HER-2. | Tamoxifen | epidermal growth factor receptor | Homo sapiens |
| 4 | ERalpha inversely correlated with EGFR expression in the tamoxifen resistant group only. | Tamoxifen | epidermal growth factor receptor | Homo sapiens |