Title : [Involvement of epidermal growth factor receptor signaling pathway in tamoxifen resistance of MCF-7 cells].

Pub. Date : 2006 Jul

PMID : 16831274






4 Functional Relationships(s)
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1 [Involvement of epidermal growth factor receptor signaling pathway in tamoxifen resistance of MCF-7 cells]. Tamoxifen epidermal growth factor receptor Homo sapiens
2 CONCLUSION: In endocrine therapy, TAM resistant breast cancer cells are likely to be generated by the activation of EGFR signaling pathway after long-term TAM treatment, and EGFR inhibitors might increase the therapeutic effects in breast cancer treatment. Tamoxifen epidermal growth factor receptor Homo sapiens
3 CONCLUSION: In endocrine therapy, TAM resistant breast cancer cells are likely to be generated by the activation of EGFR signaling pathway after long-term TAM treatment, and EGFR inhibitors might increase the therapeutic effects in breast cancer treatment. Tamoxifen epidermal growth factor receptor Homo sapiens
4 CONCLUSION: In endocrine therapy, TAM resistant breast cancer cells are likely to be generated by the activation of EGFR signaling pathway after long-term TAM treatment, and EGFR inhibitors might increase the therapeutic effects in breast cancer treatment. Tamoxifen epidermal growth factor receptor Homo sapiens