Title : Novel mechanisms of resistance to endocrine therapy: genomic and nongenomic considerations.

Pub. Date : 2006 Feb 1

PMID : 16467116






1 Functional Relationships(s)
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1 Furthermore, proline-, glutamic acid-, leucine-rich protein 1, an ER coactivator involved in both genomic and nongenomic signaling pathways, is activated by epidermal growth factor receptor and plays a prominent role in resistance to tamoxifen. Tamoxifen epidermal growth factor receptor Homo sapiens