Tamoxifen

AKT serine/threonine kinase 1 ; Homo sapiens







118 Article(s)
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101 16899133 "Nutritional and chemopreventive anti-cancer agents up-regulate expression of p27Kip1, a cyclin-dependent kinase inhibitor, in mouse JB6 epidermal and human MCF7, MDA-MB-321 and AU565 breast cancer cells". 2006 Aug 9 1
102 16951146 AKT regulation of estrogen receptor beta transcriptional activity in breast cancer. 2006 Sep 1 1
103 17010069 Targeting downstream effectors of epidermal growth factor receptor/HER2 in breast cancer with either farnesyltransferase inhibitors or mTOR antagonists. 2006 1
104 17085387 Expression of active Akt protects against tamoxifen-induced apoptosis in MCF-7 Cells. 2006 Nov 2
105 15475931 Reduced PTEN expression predicts relapse in patients with breast carcinoma treated by tamoxifen. 2005 Feb 1
106 16088978 AKT activation predicts outcome in breast cancer patients treated with tamoxifen. 2005 Oct 6
107 16172194 Antiestrogen-resistant human breast cancer cells require activated protein kinase B/Akt for growth. 2005 Sep 1
108 14990993 Tamoxifen and tamoxifen ethyl bromide induce apoptosis in acutely damaged mammary epithelial cells through modulation of AKT activity. 2004 May 6 9
109 15151944 NF-kappa B inhibition markedly enhances sensitivity of resistant breast cancer tumor cells to tamoxifen. 2004 Jun 4
110 15318929 New targets for therapy in breast cancer: mammalian target of rapamycin (mTOR) antagonists. 2004 1
111 15377841 Increased constitutive activity of PKB/Akt in tamoxifen resistant breast cancer MCF-7 cells. 2004 Sep 3
112 15585641 Inhibition of mTOR activity restores tamoxifen response in breast cancer cells with aberrant Akt Activity. 2004 Dec 1 6
113 12538508 ErbB (HER) receptors can abrogate antiestrogen action in human breast cancer by multiple signaling mechanisms. 2003 Jan 2
114 12631397 Akt kinases in breast cancer and the results of adjuvant therapy. 2003 2
115 12853346 Eicosapentaenoic acid restores tamoxifen sensitivity in breast cancer cells with high Akt activity. 2003 Jul 5
116 12970748 Effect of estradiol on estrogen receptor-alpha gene expression and activity can be modulated by the ErbB2/PI 3-K/Akt pathway. 2003 Sep 11 1
117 12479367 Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells. 2002 Jul 4
118 11139588 Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance. 2001 Mar 30 2